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Genome Integrity is a peer-reviewed journal published by BMC (BioMed Central), covering DNA Repair Mechanisms, Carcinogens and Genotoxicity Assessment, Effects of Radiation Exposure.
| Publisher | BMC (BioMed Central) |
|---|---|
| Reference style | Numbered (Vancouver) Numbered — [1], [2] in the text 1. Smith A, Jones B, Lee C. A representative article title. Genome Integrity. 2023;12(3):45–58.
Formats any DOI in Genome Integrity style. No sign-up. |
| Publishes research in | DNA Repair Mechanisms Carcinogens and Genotoxicity Assessment Effects of Radiation Exposure Telomeres, Telomerase, and Senescence Radiation Therapy and Dosimetry |
| ISSN | 2041-9414 |
| Citation impact (2-yr) | 9.5 |
| h-index | 24 |
| i10-index | 45 |
| Total citations | 2,309 |
| Top institutions publishing here | National University of Singapore |
| Journal website | www.ncbi.nlm.nih.gov |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Proper repair of DNA double strand breaks (DSBs) is vital for the preservation of genomic integrity. There are two main pathways that repair DSBs, Homologous recombination (HR) and Non-homologous end-joining (NHEJ). HR is restricted to the S and G2 phases of the cell cycle due to the requirement for the sister chromatid as a template,…
Sub-regions of hypoxia exist within all tumors and the presence of intratumoral hypoxia has an adverse impact on patient prognosis. Tumor hypoxia can increase metastatic capacity and lead to resistance to chemotherapy and radiotherapy. Hypoxia also leads to altered transcription and translation of a number of DNA damage response and repair genes. This can lead…
BACKGROUND: Investigating the cellular and molecular signatures in eukaryotic cells following exposure to nanoparticles will further our understanding on the mechanisms mediating nanoparticle induced effects. This study illustrates the molecular effects of silver nanoparticles (Ag-np) in normal human lung cells, IMR-90 and human brain cancer cells, U251 with emphasis on gene expression, induction of inflammatory…
Cellular senescence is a normal biological process that is initiated in response to a range of intrinsic and extrinsic factors that functions to remove irreparable damage and therefore potentially harmful cells, from the proliferative pool. Senescence can therefore be thought of in beneficial terms as a tumour suppressor. In contrast to this, there is a…
Ionizing radiation is an invaluable diagnostic and treatment tool used in various clinical applications. On the other hand, radiation is a known cytotoxic with a potential DNA damaging and carcinogenic effects. However, the biological effects of low and high linear energy transfer (LET) radiations are considerably more complex than previously thought. In the past decade,…
