Comparative genomic hybridization (CGH) is a powerful new method for molecular cytogenetic analysis of cancer. In a single hybridization, CGH provides an overview of DNA sequence copy number changes (losses, deletions, gains, amplifications) in a tumor specimen and maps these changes on normal chromosomes. CGH is based on the in situ hybridization of differentially labeled…
Genes Chromosomes and Cancer Template
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About the Genes Chromosomes and Cancer format
Genes Chromosomes and Cancer is a peer-reviewed journal published by Wiley, covering Cancer Genomics and Diagnostics, Genomic variations and chromosomal abnormalities, Sarcoma Diagnosis and Treatment.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Genes Chromosomes and Cancer 12 (3): 45–58.
Formats any DOI in Genes Chromosomes and Cancer style. No sign-up. |
| Publishes research in | Cancer Genomics and Diagnostics Genomic variations and chromosomal abnormalities Sarcoma Diagnosis and Treatment Acute Myeloid Leukemia Research Genetic factors in colorectal cancer |
| ISSN | 1045-2257 |
| Citation impact (2-yr) | 1.6 |
| h-index | 158 |
| i10-index | 3,388 |
| Total citations | 194,785 |
| Article processing charge | $4,840 |
| Top institutions publishing here | Lund University |
| Journal website | www3.interscience.wiley.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Genes Chromosomes and Cancer per year
Citation impact of Genes Chromosomes and Cancer by publication year
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Most-cited papers in Genes Chromosomes and Cancer
Comparative genomic hybridization (CGH) to metaphase chromosomes has been widely used for the genome-wide screening of genomic imbalances in tumor cells. Substitution of the chromosome targets by a matrix consisting of an ordered set of defined nucleic acid target sequences would greatly enhance the resolution and simplify the analysis procedure, both of which are prerequisites…
Conventional epithelioid hemangioendotheliomas (EHE) have a distinctive morphologic appearance and are characterized by a recurrent t(1;3) translocation, resulting in a WWTR1-CAMTA1 fusion gene. We have recently encountered a fusion-negative subset characterized by a somewhat different morphology, including focally well-formed vasoformative features, which was further investigated for recurrent genetic abnormalities. Based on a case showing strong…
More than 350 independent point mutations of the TP53 gene, found in a wide variety of human cancers, were compiled and analysed. From this study, we confirm the presence of four hot-spot regions which colocalize with some highly conserved domains of the protein. We also define a new hot-spot region which is observed predominantly in…
A novel polymerase chain reaction (PCR) technique has been combined with chromosome flow sorting to characterise two lymphoblastoid cell lines and one medullary thyroid carcinoma cell line carrying translocations close to the locus for multiple endocrine neoplasia type 2A (MEN 2A). Five hundred copies of the derivative chromosome(s) were flow sorted from each cell line…