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Genome Medicine is a peer-reviewed journal published by BMC (BioMed Central), covering Genomics and Rare Diseases, Cancer Genomics and Diagnostics, Genetic Associations and Epidemiology. Over its lifetime it has published 2,268 papers, which have received 149,430 citations.
| Publisher | BMC (BioMed Central) |
|---|---|
| Reference style | Numbered (Vancouver) Numbered — [1], [2] in the text 1. Smith A, Jones B, Lee C. A representative article title. Genome Medicine. 2023;12(3):45–58.
Formats any DOI in Genome Medicine style. No sign-up. |
| Publishes research in | Genomics and Rare Diseases Cancer Genomics and Diagnostics Genetic Associations and Epidemiology Single-cell and spatial transcriptomics Epigenetics and DNA Methylation |
| ISSN | 1756-994X |
| Citation impact (2-yr) | 10.45 |
| h-index | 179 |
| i10-index | 1,663 |
| Article processing charge | $3,753 |
| Open access | Yes — indexed in DOAJ |
| Top institutions publishing here | Harvard University |
| Journal website | genomemedicine.biomedcentral.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Citations each year’s papers have accumulated so far — the most recent years are still building up.
BACKGROUND: High tumor mutational burden (TMB) is an emerging biomarker of sensitivity to immune checkpoint inhibitors and has been shown to be more significantly associated with response to PD-1 and PD-L1 blockade immunotherapy than PD-1 or PD-L1 expression, as measured by immunohistochemistry (IHC). The distribution of TMB and the subset of patients with high TMB…
Humans are virtually identical in their genetic makeup, yet the small differences in our DNA give rise to tremendous phenotypic diversity across the human population. By contrast, the metagenome of the human microbiome-the total DNA content of microbes inhabiting our bodies-is quite a bit more variable, with only a third of its constituent genes found…
We introduce quanTIseq, a method to quantify the fractions of ten immune cell types from bulk RNA-sequencing data. quanTIseq was extensively validated in blood and tumor samples using simulated, flow cytometry, and immunohistochemistry data.quanTIseq analysis of 8000 tumor samples revealed that cytotoxic T cell infiltration is more strongly associated with the activation of the CXCR3/CXCL9…
Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of an individual's susceptibility to diseases. Polygenic risk scores have been widely applied in research studies,…
The human gut harbors more than 100 trillion microbial cells, which have an essential role in human metabolic regulation via their symbiotic interactions with the host. Altered gut microbial ecosystems have been associated with increased metabolic and immune disorders in animals and humans. Molecular interactions linking the gut microbiota with host energy metabolism, lipid accumulation,…
