About the Xenotransplantation format
Xenotransplantation is a peer-reviewed journal published by Wiley, covering Xenotransplantation and immune response, Animal Genetics and Reproduction, Organ Transplantation Techniques and Outcomes.
| Publisher | Wiley |
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| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text
Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Xenotransplantation 12 (3): 45–58.
Formats any DOI in Xenotransplantation style. No sign-up.
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| Publishes research in | Xenotransplantation and immune response Animal Genetics and Reproduction Organ Transplantation Techniques and Outcomes Tissue Engineering and Regenerative Medicine Pancreatic function and diabetes |
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| ISSN | 0908-665X |
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| Citation impact (2-yr) | 2.25 |
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| h-index | 82 |
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| i10-index | 1,011 |
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| Total citations | 41,313 |
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| Article processing charge | $4,120 |
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| Top institutions publishing here | Massachusetts General Hospital |
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| Journal website | onlinelibrary.wiley.com |
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| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
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Papers published in Xenotransplantation per year
Citation impact of Xenotransplantation by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in Xenotransplantation
Evaluation of human and non‐human primate antibody binding to pig cells lacking <scp>GGTA</scp>1/<scp>CMAH</scp>/β4Gal<scp>NT</scp>2 genes
José L. Estrada, Greg Martens, Ping Li et al. · 1 Mar 2015
BACKGROUND: Simultaneous inactivation of pig GGTA1 and CMAH genes eliminates carbohydrate xenoantigens recognized by human antibodies. The β4GalNT2 glycosyltransferase may also synthesize xenoantigens. To further characterize glycan-based species incompatibilities, we examined human and non-human primate antibody binding to cells derived from genetically modified pigs lacking these carbohydrate-modifying genes. METHODS: The Cas9 endonuclease and gRNA were…
Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation
Robert B. Elliott, Livia Escobar, Paul Tan et al. · 1 Mar 2007
BACKGROUND: The long-term viability and function of transplanted encapsulated neonatal porcine islets was examined in a diabetic patient. METHODS AND RESULTS: A 41-yr-old Caucasian male with type 1 diabetes for 18 yr was given an intraperitoneal transplant of alginate-encapsulated porcine islets at the dose of 15,000 islet equivalents (IEQs)/kg bodyweight (total dose 1,305,000 IEQs) via…
Double knockout pigs deficient in <scp>N</scp>‐glycolylneuraminic acid and <scp>G</scp>alactose α‐1,3‐<scp>G</scp>alactose reduce the humoral barrier to xenotransplantation
Andrew J. Lutz, Ping Li, José L. Estrada et al. · 1 Jan 2013
BACKGROUND: Clinical xenotransplantation is not possible because humans possess antibodies that recognize antigens on the surface of pig cells. Galα-1,3-Gal (Gal) and N-glycolylneuraminic acid (Neu5Gc) are two known xenoantigens. METHODS: We report the homozygous disruption of the α1, 3-galactosyltransferase (GGTA1) and the cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMAH) genes in liver-derived female pig cells using zinc-finger…
Anti‐N‐glycolylneuraminic acid antibodies identified in healthy human serum
Alex Zhu, Rosa Hurst · 4 Oct 2002
The first and major clinical obstacle in xenotransplantation is antibody-mediated hyperacute rejection. Although human natural antibodies against Galalpha1,3Gal (Gal) antigens, which are common on porcine cells and organs, have been identified to play a major role in hyperacute rejection, other natural antibodies against non-Gal epitopes may be also involved in the process. Here, we present…
Microbiological safety of the first clinical pig islet xenotransplantation trial in New Zealand
Shaun Wynyard, Divya Nathu, Olga Garkavenko et al. · 7 May 2014
BACKGROUND: Xenotransplantation using pig cells, tissues, or organs may be associated with the transmission of porcine microorganisms and the development of zoonoses. Among all porcine microorganisms porcine endogenous retroviruses (PERVs) represent a special risk because they are integrated in the genome of all pigs and able to infect human cells. In previous preclinical and retrospective…
