In this article, we review the current state of knowledge concerning the physical and chemical properties of the eumelanin pigment. We examine properties related to its photoprotective functionality, and draw the crucial link between fundamental molecular structure and observable macroscopic behaviour. Where necessary, we also briefly review certain aspects of the pheomelanin literature to draw…
Pigment Cell Research Template
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About the Pigment Cell Research format
Pigment Cell Research is a peer-reviewed journal published by Wiley, covering melanin and skin pigmentation, Biochemical Analysis and Sensing Techniques, Skin Protection and Aging.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Pigment Cell Research 12 (3): 45–58.
Formats any DOI in Pigment Cell Research style. No sign-up. |
| Publishes research in | melanin and skin pigmentation Biochemical Analysis and Sensing Techniques Skin Protection and Aging RNA regulation and disease Dyeing and Modifying Textile Fibers |
| ISSN | 0893-5785 |
| h-index | 115 |
| i10-index | 860 |
| Total citations | 58,474 |
| Top institutions publishing here | Fujita Health University |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
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Most-cited papers in Pigment Cell Research
Many modalities of treatment for acquired skin hyperpigmentation are available including chemical agents or physical therapies, but none are completely satisfactory. Depigmenting compounds should act selectively on hyperactivated melanocytes, without short- or long-term side-effects, and induce a permanent removal of undesired pigment. Since 1961 hydroquinone, a tyrosinase inhibitor, has been introduced and its therapeutic efficacy…
Compelling evidence has been gathered indicating that pro-opiomelanocortin peptides, alpha-melanocyte stimulating hormone (alpha-MSH) and adrenocorticotropic hormone (ACTH), through the cyclic AMP pathway, play a pivotal role in melanocyte differentiation and in the regulation of melanogenesis. Recently, the molecular events linking cAMP to melanogenesis up-regulation have been elucidated. This cascade involves the activation of protein kinase…
Generalized vitiligo is an autoimmune disorder characterized by acquired white patches of skin and overlying hair, the result of loss of melanocytes from involved areas. The most common disorder of pigmentation, vitiligo occurs with a frequency of 0.1-2.0% in various populations. Family clustering of cases is not uncommon, in a non-Mendelian pattern suggestive of multifactorial,…
An overview of agents causing hypopigmentation in human skin is presented. The review is organized to put forward groups of biological and chemical agents. Their mechanisms of action cover (i) tyrosinase inhibition, maturation and enhancement of its degradation; (ii) Mitf inhibition; (iii) downregulation of MC1R activity; (iv) interference with melanosome maturation and transfer; (v) melanocyte…