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Quantitative Biology is a peer-reviewed journal published by Springer Nature, covering Gene Regulatory Network Analysis, Bioinformatics and Genomic Networks, Single-cell and spatial transcriptomics.
| Publisher | Springer Nature |
|---|---|
| Reference style | Superscript numbered (Nature) Superscript — small raised numerals in the text 1. Smith, A., Jones, B. & Lee, C. A representative article title. Quantitative Biology 12, 45–58 (2023).
Formats any DOI in Quantitative Biology style. No sign-up. |
| Publishes research in | Gene Regulatory Network Analysis Bioinformatics and Genomic Networks Single-cell and spatial transcriptomics Genomics and Phylogenetic Studies Computational Drug Discovery Methods |
| ISSN | 2095-4689 |
| Citation impact (2-yr) | 2.97 |
| h-index | 33 |
| i10-index | 121 |
| Total citations | 6,663 |
| Open access | Yes |
| Top institutions publishing here | Tsinghua University |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Citations each year’s papers have accumulated so far — the most recent years are still building up.
BACKGROUND: The recent development of metagenomic sequencing makes it possible to massively sequence microbial genomes including viral genomes without the need for laboratory culture. Existing reference-based and gene homology-based methods are not efficient in identifying unknown viruses or short viral sequences from metagenomic data. METHODS: Here we developed a reference-free and alignment-free machine learning method,…
Background In recent years, since the molecular docking technique can greatly improve the efficiency and reduce the research cost, it has become a key tool in computer‐assisted drug design to predict the binding affinity and analyze the interactive mode. Results This study introduces the key principles, procedures and the widely‐used applications for molecular docking. Also,…
Background: The coronavirus disease 2019 (COVID-19) is rapidly spreading in China and more than 30 countries over last two months. COVID-19 has multiple characteristics distinct from other infectious diseases, including high infectivity during incubation, time delay between real dynamics and daily observed number of confirmed cases, and the intervention effects of implemented quarantine and control…
The CRISPR-Cas9 system, naturally a defense mechanism in prokaryotes, has been repurposed as an RNA-guided DNA targeting platform. It has been widely used for genome editing and transcriptome modulation, and has shown great promise in correcting mutations in human genetic diseases. Off-target effects are a critical issue for all of these applications. Here we review…
Background Many existing bioinformatics predictors are based on machine learning technology. When applying these predictors in practical studies, their predictive performances should be well understood. Different performance measures are applied in various studies as well as different evaluation methods. Even for the same performance measure, different terms, nomenclatures or notations may appear in different context.…
