PLOS

PLOS Medicine Template

Write in a clean editor, then format for PLOS Medicine in one click — DocuGuru applies the official PLOS template with numbered references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.

About the PLOS Medicine format

PLOS Medicine is a peer-reviewed journal published by PLOS, covering HIV/AIDS Research and Interventions, Global Maternal and Child Health, Malaria Research and Control. Over its lifetime it has published 5,815 papers, which have received 780,526 citations.

PublisherPLOS
Reference styleNumbered (Vancouver)
Numbered — [1], [2] in the text
1. Smith A, Jones B, Lee C. A representative article title. PLOS Medicine. 2023;12(3):45–58.

Formats any DOI in PLOS Medicine style. No sign-up.

Publishes research inHIV/AIDS Research and Interventions Global Maternal and Child Health Malaria Research and Control Child Nutrition and Water Access Health Systems, Economic Evaluations, Quality of Life
ISSN1549-1277
Citation impact (2-yr)7.8
h-index353
i10-index4,291
Article processing charge$5,300
Open accessYes — indexed in DOAJ
Top institutions publishing hereHarvard University
Journal websitewww.plosmedicine.org
You getA submission-ready PDF and the editable LaTeX source — ready to submit.

Papers published in PLOS Medicine per year

198
2014
157
2015
275
2016
277
2017
241
2018
292
2019
345
2020
335
2021
237
2022
174
2023
158
2024
195
2025

Citation impact of PLOS Medicine by publication year

27.6K
2014
40.7K
2015
36.5K
2016
28.3K
2017
30.4K
2018
23.6K
2019
31K
2020
24.3K
2021
10.6K
2022
5.3K
2023
2.5K
2024
1.1K
2025

Citations each year’s papers have accumulated so far — the most recent years are still building up.

Most-cited papers in PLOS Medicine

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies

Erik von Elm, Douglas G. Altman, Matthias Egger et al. · 10 Oct 2007

Much biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study's generalisability. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Initiative developed recommendations on what should be included in an accurate and complete report of an observational study.…

21,784 citations Cite SaveGo to paper →
Projections of Global Mortality and Burden of Disease from 2002 to 2030

Colin Mathers, Dejan Lončar · 22 Nov 2006

BACKGROUND: Global and regional projections of mortality and burden of disease by cause for the years 2000, 2010, and 2030 were published by Murray and Lopez in 1996 as part of the Global Burden of Disease project. These projections, which are based on 1990 data, continue to be widely quoted, although they are substantially outdated;…

11,521 citations Cite SaveGo to paper →
Why Most Published Research Findings Are False

John P. A. Ioannidis · 2 Aug 2005

There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this…

10,610 citations Cite SaveGo to paper →
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration

Jan P. Vandenbroucke, Erik von Elm, Douglas G. Altman et al. · 10 Oct 2007

Much medical research is observational. The reporting of observational studies is often of insufficient quality. Poor reporting hampers the assessment of the strengths and weaknesses of a study and the generalisability of its results. Taking into account empirical evidence and theoretical considerations, a group of methodologists, researchers, and editors developed the Strengthening the Reporting of…

8,479 citations Cite SaveGo to paper →

PLOS Medicine template — frequently asked questions

How do I write a paper in the PLOS Medicine format?
In DocuGuru you write your manuscript in a normal editor — no LaTeX setup required — and select the PLOS Medicine template. When you export, DocuGuru compiles the paper into the official PLOS format and hands you a submission-ready PDF along with the editable LaTeX source.
What reference style does PLOS Medicine use?
PLOS Medicine uses Numbered (Vancouver) references, shown as numbered [1], [2] markers in the text. DocuGuru formats every in-text citation and the reference list in this exact style automatically. A reference appears like this: 1. Smith A, Jones B, Lee C. A representative article title. PLOS Medicine. 2023;12(3):45–58.
Do I need to know LaTeX to submit to PLOS Medicine?
No. DocuGuru generates the article LaTeX class and compiles the PDF for you in the background, so you get a PLOS-ready PLOS Medicine document without writing any LaTeX. If you do want it, the LaTeX source is included in the export.
Can I import an existing draft into the PLOS Medicine template?
Yes. Paste or upload your current manuscript — Word, LaTeX, Markdown, or plain text — and DocuGuru reflows it into the PLOS Medicine format with correct headings, figures, tables, and numbered citations.
What is PLOS Medicine?
PLOS Medicine publishes high-impact research that transforms healthcare delivery, shapes policy, and advances clinical understanding. It is a life sciences and medicine journal, published by PLOS.
Can I export a submission-ready PLOS Medicine PDF?
Yes — DocuGuru produces a PDF built with the official PLOS Medicine template (the article class) that is ready to submit to PLOS, together with the matching LaTeX source files.
How much does the PLOS Medicine template cost?
You can start writing in the PLOS Medicine template for free. Exporting the final submission-ready PLOS Medicine PDF and LaTeX source is part of DocuGuru's paid plans — see the app for current pricing.
Use the PLOS Medicine template