PLOS

PLOS ONE Template

Write in a clean editor, then format for PLOS ONE in one click — DocuGuru applies the official PLOS template with numbered references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.

About the PLOS ONE format

PLOS ONE is a peer-reviewed journal published by PLOS, covering HIV/AIDS Research and Interventions, Plant and animal studies, HIV Research and Treatment. Over its lifetime it has published 341,943 papers, which have received 12,486,974 citations.

PublisherPLOS
Reference styleNumbered (Vancouver)
Numbered — [1], [2] in the text
1. Smith A, Jones B, Lee C. A representative article title. PLOS ONE. 2023;12(3):45–58.

Formats any DOI in PLOS ONE style. No sign-up.

Publishes research inHIV/AIDS Research and Interventions Plant and animal studies HIV Research and Treatment Global Maternal and Child Health Genomics and Phylogenetic Studies
ISSN1932-6203
Citation impact (2-yr)2.94
h-index599
i10-index234,136
Article processing charge$1,805
Open accessYes — indexed in DOAJ
Top institutions publishing hereCentre National de la Recherche Scientifique
Journal websitewww.plosone.org
You getA submission-ready PDF and the editable LaTeX source — ready to submit.

Papers published in PLOS ONE per year

32.1K
2014
29.9K
2015
23.1K
2016
21.2K
2017
18.9K
2018
16.2K
2019
16.7K
2020
16.6K
2021
16.1K
2022
15.1K
2023
17.9K
2024
19.6K
2025

Citation impact of PLOS ONE by publication year

1.5M
2014
1.3M
2015
914.8K
2016
812.6K
2017
628.2K
2018
482.8K
2019
469.6K
2020
367.1K
2021
226.1K
2022
142.5K
2023
91.7K
2024
36.5K
2025

Citations each year’s papers have accumulated so far — the most recent years are still building up.

Most-cited papers in PLOS ONE

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

Paul J. McMurdie, Susan Holmes · 22 Apr 2013

BACKGROUND: the analysis of microbial communities through dna sequencing brings many challenges: the integration of different types of data with methods from ecology, genetics, phylogenetics, multivariate statistics, visualization and testing. With the increased breadth of experimental designs now being pursued, project-specific statistical analyses are often needed, and these analyses are often difficult (or impossible) for…

22,788 citations Cite SaveGo to paper →
FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

Morgan N. Price, Paramvir Dehal, Adam P. Arkin · 9 Mar 2010

BACKGROUND: We recently described FastTree, a tool for inferring phylogenies for alignments with up to hundreds of thousands of sequences. Here, we describe improvements to FastTree that improve its accuracy without sacrificing scalability. METHODOLOGY/PRINCIPAL FINDINGS: Where FastTree 1 used nearest-neighbor interchanges (NNIs) and the minimum-evolution criterion to improve the tree, FastTree 2 adds minimum-evolution subtree-pruning-regrafting…

16,116 citations Cite SaveGo to paper →
Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement

Bruce J. Walker, Thomas Abeel, Terrance Shea et al. · 19 Nov 2014

Advances in modern sequencing technologies allow us to generate sufficient data to analyze hundreds of bacterial genomes from a single machine in a single day. This potential for sequencing massive numbers of genomes calls for fully automated methods to produce high-quality assemblies and variant calls. We introduce Pilon, a fully automated, all-in-one tool for correcting…

10,348 citations Cite SaveGo to paper →
REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

Fran Supek, Matko Bošnjak, Nives Škunca et al. · 18 Jul 2011

Outcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO). The resulting lists of GO terms may be large and highly redundant, and thus difficult to interpret.REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative…

7,003 citations Cite SaveGo to paper →
A Robust, Simple Genotyping-by-Sequencing (GBS) Approach for High Diversity Species

Robert J. Elshire, Jeffrey C. Glaubitz, Qi Sun et al. · 4 May 2011

Advances in next generation technologies have driven the costs of DNA sequencing down to the point that genotyping-by-sequencing (GBS) is now feasible for high diversity, large genome species. Here, we report a procedure for constructing GBS libraries based on reducing genome complexity with restriction enzymes (REs). This approach is simple, quick, extremely specific, highly reproducible,…

6,804 citations Cite SaveGo to paper →

PLOS ONE template — frequently asked questions

How do I write a paper in the PLOS ONE format?
In DocuGuru you write your manuscript in a normal editor — no LaTeX setup required — and select the PLOS ONE template. When you export, DocuGuru compiles the paper into the official PLOS format and hands you a submission-ready PDF along with the editable LaTeX source.
What reference style does PLOS ONE use?
PLOS ONE uses Numbered (Vancouver) references, shown as numbered [1], [2] markers in the text. DocuGuru formats every in-text citation and the reference list in this exact style automatically. A reference appears like this: 1. Smith A, Jones B, Lee C. A representative article title. PLOS ONE. 2023;12(3):45–58.
Do I need to know LaTeX to submit to PLOS ONE?
No. DocuGuru generates the article LaTeX class and compiles the PDF for you in the background, so you get a PLOS-ready PLOS ONE document without writing any LaTeX. If you do want it, the LaTeX source is included in the export.
Can I import an existing draft into the PLOS ONE template?
Yes. Paste or upload your current manuscript — Word, LaTeX, Markdown, or plain text — and DocuGuru reflows it into the PLOS ONE format with correct headings, figures, tables, and numbered citations.
What is PLOS ONE?
PLOS ONE is an inclusive, open-access journal spanning all areas of science. It is a life sciences and medicine journal, published by PLOS.
Can I export a submission-ready PLOS ONE PDF?
Yes — DocuGuru produces a PDF built with the official PLOS ONE template (the article class) that is ready to submit to PLOS, together with the matching LaTeX source files.
How much does the PLOS ONE template cost?
You can start writing in the PLOS ONE template for free. Exporting the final submission-ready PLOS ONE PDF and LaTeX source is part of DocuGuru's paid plans — see the app for current pricing.
Use the PLOS ONE template