PLOS

PLoS Clinical Trials Template

Write in a clean editor, then format for PLoS Clinical Trials in one click — DocuGuru applies the official PLOS template with numbered references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.

About the PLoS Clinical Trials format

PLoS Clinical Trials is a peer-reviewed journal published by PLOS, covering Malaria Research and Control, HIV/AIDS Research and Interventions, HIV Research and Treatment.

PublisherPLOS
Reference styleNumbered (Vancouver)
Numbered — [1], [2] in the text
1. Smith A, Jones B, Lee C. A representative article title. PLoS Clinical Trials. 2023;12(3):45–58.

Formats any DOI in PLoS Clinical Trials style. No sign-up.

Publishes research inMalaria Research and Control HIV/AIDS Research and Interventions HIV Research and Treatment Meta-analysis and systematic reviews Inflammatory mediators and NSAID effects
ISSN1555-5887
h-index32
i10-index54
Total citations3,675
Top institutions publishing hereLondon School of Hygiene & Tropical Medicine
Journal websitewww.pubmedcentral.nih.gov
You getA submission-ready PDF and the editable LaTeX source — ready to submit.

Papers published in PLoS Clinical Trials per year

1
1993
1
2005
41
2006
28
2007

Citation impact of PLoS Clinical Trials by publication year

0
1993
0
2005
2.4K
2006
1.3K
2007

Citations each year’s papers have accumulated so far — the most recent years are still building up.

Most-cited papers in PLoS Clinical Trials

Factors That Can Affect the External Validity of Randomised Controlled Trials

Peter M. Rothwell · 19 May 2006

Citation: Rothwell, P. M. (2006). 'Factors that can affect the external validity of randomised controlled trials' PLoS Clinical Trials, 1(1): e9. [Available at http://clinicaltrials.ploshubs.org]. Copyright 2006 Peter M. Rothwell. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided…

Tenofovir Disoproxil Fumarate for Prevention of HIV Infection in Women: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Trial

Leigh Peterson, Doug Taylor, Ronald E. Roddy et al. · 23 May 2007

OBJECTIVES: The objective of this trial was to investigate the safety and preliminary effectiveness of a daily dose of 300 mg of tenofovir disoproxil fumarate (TDF) versus placebo in preventing HIV infection in women. DESIGN: This was a phase 2, randomized, double-blind, placebo-controlled trial. SETTING: The study was conducted between June 2004 and March 2006…

Cardiovascular and Cerebrovascular Events in the Randomized, Controlled Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)

ADAPT Research Group · 14 Nov 2006

OBJECTIVES: The Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT) was designed to evaluate the conventional NSAID naproxen sodium and the selective COX-2 inhibitor celecoxib for primary prevention of Alzheimer's dementia (AD). On 17 December 2004, after the Adenoma Prevention with Celecoxib (APC) trial reported increased cardiovascular risks with celecoxib, the ADAPT Steering Committee suspended treatment and…

Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A Randomized Trial

Moses R. Kamya, Adoke Yeka, Hasifa Bukirwa et al. · 15 May 2007

OBJECTIVES: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. DESIGN: Randomized single-blinded clinical trial. SETTING: Apac, Uganda, an area of very high malaria transmission intensity. PARTICIPANTS: Children aged 6 mo to 10 y with uncomplicated falciparum malaria. INTERVENTION: Treatment of malaria with AL or…

A Phase 2b Randomised Trial of the Candidate Malaria Vaccines FP9 ME-TRAP and MVA ME-TRAP among Children in Kenya

Philip Bejon, Jedidah Mwacharo, Oscar Kai et al. · 18 Oct 2006

OBJECTIVE: The objective was to measure the efficacy of the vaccination regimen FFM ME-TRAP in preventing episodes of clinical malaria among children in a malaria endemic area. FFM ME-TRAP is sequential immunisation with two attenuated poxvirus vectors (FP9 and modified vaccinia virus Ankara), which both deliver the pre-erythrocytic malaria antigen construct multiple epitope-thrombospondin-related adhesion protein…

PLoS Clinical Trials template — frequently asked questions

How do I write a paper in the PLoS Clinical Trials format?
In DocuGuru you write your manuscript in a normal editor — no LaTeX setup required — and select the PLoS Clinical Trials template. When you export, DocuGuru compiles the paper into the official PLOS format and hands you a submission-ready PDF along with the editable LaTeX source.
What reference style does PLoS Clinical Trials use?
PLoS Clinical Trials uses Numbered (Vancouver) references, shown as numbered [1], [2] markers in the text. DocuGuru formats every in-text citation and the reference list in this exact style automatically. A reference appears like this: 1. Smith A, Jones B, Lee C. A representative article title. PLoS Clinical Trials. 2023;12(3):45–58.
Do I need to know LaTeX to submit to PLoS Clinical Trials?
No. DocuGuru generates the article LaTeX class and compiles the PDF for you in the background, so you get a PLOS-ready PLoS Clinical Trials document without writing any LaTeX. If you do want it, the LaTeX source is included in the export.
Can I import an existing draft into the PLoS Clinical Trials template?
Yes. Paste or upload your current manuscript — Word, LaTeX, Markdown, or plain text — and DocuGuru reflows it into the PLoS Clinical Trials format with correct headings, figures, tables, and numbered citations.
Who publishes PLoS Clinical Trials?
PLoS Clinical Trials is a life sciences and medicine journal published by PLOS. DocuGuru's PLoS Clinical Trials template matches PLOS's official submission format.
Can I export a submission-ready PLoS Clinical Trials PDF?
Yes — DocuGuru produces a PDF built with the official PLoS Clinical Trials template (the article class) that is ready to submit to PLOS, together with the matching LaTeX source files.
How much does the PLoS Clinical Trials template cost?
You can start writing in the PLoS Clinical Trials template for free. Exporting the final submission-ready PLoS Clinical Trials PDF and LaTeX source is part of DocuGuru's paid plans — see the app for current pricing.
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