BMC (BioMed Central)

Biology Direct Template

Write in a clean editor, then format for Biology Direct in one click — DocuGuru applies the official BMC (BioMed Central) template with numbered references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.

About the Biology Direct format

Biology Direct is a peer-reviewed journal published by BMC (BioMed Central), covering RNA and protein synthesis mechanisms, Genomics and Phylogenetic Studies, Ferroptosis and cancer prognosis. Over its lifetime it has published 1,294 papers, which have received 46,249 citations.

PublisherBMC (BioMed Central)
Reference styleNumbered (Vancouver)
Numbered — [1], [2] in the text
1. Smith A, Jones B, Lee C. A representative article title. Biology Direct. 2023;12(3):45–58.

Formats any DOI in Biology Direct style. No sign-up.

Publishes research inRNA and protein synthesis mechanisms Genomics and Phylogenetic Studies Ferroptosis and cancer prognosis Cancer-related molecular mechanisms research Bacterial Genetics and Biotechnology
ISSN1745-6150
Citation impact (2-yr)4.02
h-index102
i10-index736
Article processing charge$2,195
Open accessYes — indexed in DOAJ
Top institutions publishing hereNational Center for Biotechnology Information
Journal websitewww.biology-direct.com
You getA submission-ready PDF and the editable LaTeX source — ready to submit.

Papers published in Biology Direct per year

35
2014
70
2015
69
2016
31
2017
27
2018
24
2019
29
2020
27
2021
42
2022
86
2023
147
2024
125
2025

Citation impact of Biology Direct by publication year

1.3K
2014
3.1K
2015
2.3K
2016
1.2K
2017
724
2018
684
2019
1.5K
2020
1K
2021
771
2022
1.4K
2023
1.2K
2024
447
2025

Citations each year’s papers have accumulated so far — the most recent years are still building up.

Most-cited papers in Biology Direct

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

Kira S. Makarova, Nick V. Grishin, Svetlana A. Shabalina et al. · 16 Mar 2006

BACKGROUND: All archaeal and many bacterial genomes contain Clustered Regularly Interspaced Short Palindrome Repeats (CRISPR) and variable arrays of the CRISPR-associated (cas) genes that have been previously implicated in a novel form of DNA repair on the basis of comparative analysis of their protein product sequences. However, the proximity of CRISPR and cas genes strongly…

1,188 citations Cite SaveGo to paper →
Domain enhanced lookup time accelerated BLAST

Grzegorz M. Boratyn, Alejandro A. Schäffer, Richa Agarwala et al. · 1 Jan 2012

BACKGROUND: BLAST is a commonly-used software package for comparing a query sequence to a database of known sequences; in this study, we focus on protein sequences. Position-specific-iterated BLAST (PSI-BLAST) iteratively searches a protein sequence database, using the matches in round i to construct a position-specific score matrix (PSSM) for searching the database in round i…

Designing of interferon-gamma inducing MHC class-II binders

Sandeep Kumar Dhanda, Pooja Vir, Gajendra P. S. Raghava · 1 Dec 2013

BACKGROUND: The generation of interferon-gamma (IFN-γ) by MHC class II activated CD4+ T helper cells play a substantial contribution in the control of infections such as caused by Mycobacterium tuberculosis. In the past, numerous methods have been developed for predicting MHC class II binders that can activate T-helper cells. Best of author's knowledge, no method…

The ancient Virus World and evolution of cells.

Eugene V. Koonin, Tatiana G. Senkevich, Valerian V. Dolja · 1 Jan 2006

BACKGROUND: Recent advances in genomics of viruses and cellular life forms have greatly stimulated interest in the origins and evolution of viruses and, for the first time, offer an opportunity for a data-driven exploration of the deepest roots of viruses. Here we briefly review the current views of virus evolution and propose a new, coherent…

CAIcal: A combined set of tools to assess codon usage adaptation

Pere Puigbò, Ignacio G. Bravo, Santiago Garcı́a-Vallvé · 1 Jan 2008

BACKGROUND: The Codon Adaptation Index (CAI) was first developed to measure the synonymous codon usage bias for a DNA or RNA sequence. The CAI quantifies the similarity between the synonymous codon usage of a gene and the synonymous codon frequency of a reference set. RESULTS: We describe here CAIcal, a web-server available at http://genomes.urv.es/CAIcal that…

Biology Direct template — frequently asked questions

How do I write a paper in the Biology Direct format?
In DocuGuru you write your manuscript in a normal editor — no LaTeX setup required — and select the Biology Direct template. When you export, DocuGuru compiles the paper into the official BMC (BioMed Central) format and hands you a submission-ready PDF along with the editable LaTeX source.
What reference style does Biology Direct use?
Biology Direct uses Numbered (Vancouver) references, shown as numbered [1], [2] markers in the text. DocuGuru formats every in-text citation and the reference list in this exact style automatically. A reference appears like this: 1. Smith A, Jones B, Lee C. A representative article title. Biology Direct. 2023;12(3):45–58.
Do I need to know LaTeX to submit to Biology Direct?
No. DocuGuru generates the bmcart LaTeX class and compiles the PDF for you in the background, so you get a BMC (BioMed Central)-ready Biology Direct document without writing any LaTeX. If you do want it, the LaTeX source is included in the export.
Can I import an existing draft into the Biology Direct template?
Yes. Paste or upload your current manuscript — Word, LaTeX, Markdown, or plain text — and DocuGuru reflows it into the Biology Direct format with correct headings, figures, tables, and numbered citations.
What is Biology Direct?
BMC / BioMed Central journal. It is a life sciences and medicine journal, published by BMC (BioMed Central).
Can I export a submission-ready Biology Direct PDF?
Yes — DocuGuru produces a PDF built with the official Biology Direct template (the bmcart class) that is ready to submit to BMC (BioMed Central), together with the matching LaTeX source files.
How much does the Biology Direct template cost?
You can start writing in the Biology Direct template for free. Exporting the final submission-ready Biology Direct PDF and LaTeX source is part of DocuGuru's paid plans — see the app for current pricing.
Use the Biology Direct template