BACKGROUND: The relatively high transfection efficiency of polyethylenimine (PEI) vectors has been hypothesized to be due to their ability to avoid trafficking to degradative lysosomes. According to the proton sponge hypothesis, the buffering capacity of PEI leads to osmotic swelling and rupture of endosomes, resulting in the release of the vector into the cytoplasm. METHODS:…
The Journal of Gene Medicine Template
Write in a clean editor, then format for The Journal of Gene Medicine in one click — DocuGuru applies the official Wiley template with author–year references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.
About the The Journal of Gene Medicine format
The Journal of Gene Medicine is a peer-reviewed journal published by Wiley, covering Virus-based gene therapy research, RNA Interference and Gene Delivery, Human auditory perception and evaluation.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." The Journal of Gene Medicine 12 (3): 45–58.
Formats any DOI in The Journal of Gene Medicine style. No sign-up. |
| Publishes research in | Virus-based gene therapy research RNA Interference and Gene Delivery Human auditory perception and evaluation Educational Robotics and Engineering Diverse Scientific and Economic Studies |
| ISSN | 1099-498X |
| Citation impact (2-yr) | 2.6 |
| h-index | 108 |
| i10-index | 1,518 |
| Total citations | 73,401 |
| Article processing charge | $4,070 |
| Top institutions publishing here | Centre National de la Recherche Scientifique |
| Journal website | onlinelibrary.wiley.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in The Journal of Gene Medicine per year
Citation impact of The Journal of Gene Medicine by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in The Journal of Gene Medicine
To date, over 1800 gene therapy clinical trials have been completed, are ongoing or have been approved worldwide. Our database brings together global information on gene therapy clinical trials from official agency sources, published literature, conference presentations and posters kindly provided to us by individual investigators or trial sponsors. This review presents our analysis of…
The continually increasing wealth of knowledge about the role of genes involved in acquired or hereditary diseases renders the delivery of regulatory genes or nucleic acids into affected cells a potentially promising strategy. Apart from viral vectors, non-viral gene delivery systems have recently received increasing interest, due to safety concerns associated with insertional mutagenesis of…
To date, almost 2600 gene therapy clinical trials have been completed, are ongoing or have been approved worldwide. Our database brings together global information on gene therapy clinical activity from trial databases, official agency sources, published literature, conference presentations and posters kindly provided to us by individual investigators or trial sponsors. This review presents our…
BACKGROUND: Efficient gene transfer is a major challenge for non-viral gene therapy. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy. METHODS: Linear or branched polyethylenimine (PEI)/DNA complexes were generated in varying salt conditions and their transfection efficiencies were compared in vitro and in vivo…