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Proteoglycan Research is a peer-reviewed journal published by Wiley, covering Proteoglycans and glycosaminoglycans research, Glycosylation and Glycoproteins Research, Cell Adhesion Molecules Research.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Proteoglycan Research 12 (3): 45–58.
Formats any DOI in Proteoglycan Research style. No sign-up. |
| Publishes research in | Proteoglycans and glycosaminoglycans research Glycosylation and Glycoproteins Research Cell Adhesion Molecules Research Connective tissue disorders research Protease and Inhibitor Mechanisms |
| ISSN | 2832-3556 |
| Citation impact (2-yr) | 2.38 |
| h-index | 10 |
| i10-index | 11 |
| Total citations | 305 |
| Top institutions publishing here | Thomas Jefferson University |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Heparanase (Hpa1) is expressed by tumor cells and cells of the tumor microenvironment and functions extracellularly to remodel the extracellular matrix (ECM) and regulate the bioavailability of ECM-bound factors, augmenting, among other effects, gene transcription, autophagy, exosome formation, and heparan sulfate (HS) turnover. Much of the impact of heparanase on tumor progression is related to…
Abstract The integral membrane protein CD44 is constitutively expressed in most tissues, and is the primary cell surface receptor for hyaluronan (HA). HA is the key scaffolding organizer of proteoglycans and receptors in the extracellular matrix. CD44 is expressed as cell type‐specific and context‐specific alternatively spliced isoforms with variable glycosylation and interreceptor interactions. CD44 plays…
Abstract Glypicans are a family of proteoglycans that are bound to the cell surface by a glycosylphosphatidylinositol anchor. These proteoglycans are highly conserved during evolution, and the mammalian genome contains six members of the family. Glypicans carry two to four heparan sulfate chains that are inserted near the carboxy terminus. The crystal structure reveals a…
Abstract Proteoglycans (PGs) are a diverse class of glycoconjugates that serve critical functions in normal mechanobiology and mechanopathology. Both the protein cores and attached glycosaminoglycan (GAG) chains function in mechanically sensitive processes, and loss of either can contribute to development of pathological conditions. PGs function as key components of the extracellular matrix (ECM), where they…
Anti-angiogenic therapy is an established method for the treatment of several cancers and vascular-related diseases. Most of the agents employed target the vascular endothelial growth factor A, the major cytokine stimulating angiogenesis. However, the efficacy of these treatments is limited by the onset of drug resistance. Therefore, it is of fundamental importance to better understand…
