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Current Protocols in Pharmacology is a peer-reviewed journal published by Wiley, covering Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Ion channel regulation and function.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Current Protocols in Pharmacology 12 (3): 45–58.
Formats any DOI in Current Protocols in Pharmacology style. No sign-up. |
| Publishes research in | Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology Research Ion channel regulation and function Neuropeptides and Animal Physiology Neurotransmitter Receptor Influence on Behavior |
| ISSN | 1934-8282 |
| h-index | 52 |
| i10-index | 172 |
| Total citations | 12,798 |
| Article processing charge | $5,050 |
| Top institutions publishing here | Abbott Fund |
| Journal website | currentprotocols.onlinelibrary.wiley.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
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Streptozotocin (STZ) is an antibiotic that produces pancreatic islet β-cell destruction and is widely used experimentally to produce a model of type 1 diabetes mellitus (T1DM). Detailed in this unit are protocols for producing STZ-induced insulin deficiency and hyperglycemia in mice and rats. Also described are protocols for creating animal models for type 2 diabetes…
The development of antidepressants requires simple rodent behavioral tests for initial screening before undertaking more complex preclinical tests and clinical evaluation. Presented in the unit are two widely used screening tests used for antidepressants, the forced swim (also termed behavioral despair) test in the rat and mouse, and the tail suspension test in the mouse.…
A biomarker is a biological observation that substitutes for and ideally predicts a clinically relevant endpoint or intermediate outcome that is more difficult to observe. The use of clinical biomarkers is easier and less expensive than direct measurement of the final clinical endpoint, and biomarkers are usually measured over a shorter time span. They can…
Streptozotocin (STZ) is an antibiotic that can cause pancreatic β-cell destruction, so it is widely used experimentally as an agent capable of inducing insulin-dependent diabetes mellitus (IDDM), also known as type 1 diabetes mellitus (T1DM). This unit describes protocols for the production of insulin deficiency and hyperglycemia in mice and rats, using STZ. These models…
The focus of this overview is on the animal models of obesity most commonly utilized in research. The models include monogenic models in the leptin pathway, polygenic diet-dependent models, and, in particular for their historical perspective, surgical and chemical models of obesity. However, there are far too many models to consider all of them comprehensively,…
