Fluorinated compounds are synthesized in pharmaceutical research on a routine basis and many marketed compounds contain fluorine. The present review summarizes some of the most frequently employed strategies for using fluorine substituents in medicinal chemistry. Quite often, fluorine is introduced to improve the metabolic stability by blocking metabolically labile sites. However, fluorine can also be…
ChemBioChem Template
Write in a clean editor, then format for ChemBioChem in one click — DocuGuru applies the official Wiley template with author–year references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.
About the ChemBioChem format
ChemBioChem is a peer-reviewed journal published by Wiley, covering Advanced biosensing and bioanalysis techniques, Chemical Synthesis and Analysis, DNA and Nucleic Acid Chemistry.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." ChemBioChem 12 (3): 45–58.
Formats any DOI in ChemBioChem style. No sign-up. |
| Publishes research in | Advanced biosensing and bioanalysis techniques Chemical Synthesis and Analysis DNA and Nucleic Acid Chemistry Click Chemistry and Applications RNA and protein synthesis mechanisms |
| ISSN | 1439-4227 |
| Citation impact (2-yr) | 2.6 |
| h-index | 161 |
| i10-index | 5,709 |
| Total citations | 265,208 |
| Article processing charge | $4,020 |
| Top institutions publishing here | Centre National de la Recherche Scientifique |
| Journal website | www.chembiochem.org |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in ChemBioChem per year
Citation impact of ChemBioChem by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in ChemBioChem
The task of inventing and developing active ingredients with useful biological activities requires a search for novel chemical substructures. This process may trigger the discovery of whole classes of chemicals of potential commercial interest. Similar biological effects can often be achieved by completely different compounds. However, compounds within a given structural family may exhibit quite…
Fungi or bacteria that produce secondary metabolites often have the potential to bring up various compounds from a single strain. The molecular basis for this well-known observation was confirmed in the last few years by several sequencing projects of different microorganisms. Besides well-known examples about induction of a selected biosynthesis (for example, by high- or…
With the current trajectory of the 2019-nCoV outbreak unknown, public health and medicinal measures will both be needed to contain spreading of the virus and to optimize patient outcomes. Although little is known about the virus, an examination of the genome sequence shows strong homology with its better-studied cousin, SARS-CoV. The spike protein used for…
Hydrogen is an important metabolite for many microrganisms. H2 is either produced or consumed by hydrogenase enzymes, according to the reaction: H2⇌2 H+ + 2 e−. The catalytic sites of the two major families of hydrogenases include a dinuclear center, either NiFe (see picture) or FeFe, along with proteic and nonproteic ligands. The structure and…