Obesity is a significant risk factor for developing osteoarthritis in weight-bearing and non-weight-bearing joints. Although the pathogenesis of obesity-associated osteoarthritis is not completely understood, recent studies indicate that pro-inflammatory metabolic factors contribute to an increase in osteoarthritis risk. Adipose tissue, and in particular infrapatellar fat, is a local source of pro-inflammatory mediators that are increased…
Pathobiology of Aging & Age-related Diseases Template
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About the Pathobiology of Aging & Age-related Diseases format
Pathobiology of Aging & Age-related Diseases is a peer-reviewed journal published by Taylor & Francis, covering Genetics, Aging, and Longevity in Model Organisms, Adipose Tissue and Metabolism, Mitochondrial Function and Pathology.
| Publisher | Taylor & Francis |
|---|---|
| Reference style | Author–year (Chicago, T&F) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Pathobiology of Aging & Age-related Diseases 12 (3): 45–58.
Formats any DOI in Pathobiology of Aging & Age-related Diseases style. No sign-up. |
| Publishes research in | Genetics, Aging, and Longevity in Model Organisms Adipose Tissue and Metabolism Mitochondrial Function and Pathology Alzheimer's disease research and treatments Muscle Physiology and Disorders |
| ISSN | 2001-0001 |
| h-index | 23 |
| i10-index | 44 |
| Total citations | 1,797 |
| Top institutions publishing here | University of Washington |
| Journal website | www.pathobiologyofaging.net |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Pathobiology of Aging & Age-related Diseases per year
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Most-cited papers in Pathobiology of Aging & Age-related Diseases
Old mice will have a subset of lesions as part of the progressive decline in organ function that defines aging. External and palpable lesions will be noted by the research, husbandry, or veterinary staff during testing, cage changing, or physical exams. While these readily observable lesions may cause alarm, not all cause undue distress or…
Cellular senescence is a state of permanent growth arrest and is thought to play a pivotal role in tumor suppression. Cellular senescence may play an important role in tumor suppression, wound healing, and protection against tissue fibrosis in physiological conditions in vivo. However, accumulating evidence that senescent cells may have harmful effects in vivo and…
Zinc plays an essential role in many biochemical pathways and participates in several cell functions, including the immune response. This review describes the role of zinc in human health, aging, and immunosenescence. Zinc deficiency is frequent in the elderly and leads to changes similar to those that occur in oxidative inflammatory aging (oxi-inflamm-aging) and immunosenescence.…
Genome maintenance is considered a prime longevity assurance mechanism as apparent from many progeroid human syndromes that are caused by genome maintenance defects. The ERCC1 protein is involved in three genome maintenance systems: nucleotide excision repair, interstrand cross-link repair, and homologous recombination. Here we describe in-life and post-mortem observations for a hypomorphic Ercc1 variant, Ercc1(-/Δ7),…