Here, we propose a new model for understanding the Warburg effect in tumor metabolism. Our hypothesis is that epithelial cancer cells induce the Warburg effect (aerobic glycolysis) in neighboring stromal fibroblasts. These cancer-associated fibroblasts, then undergo myo-fibroblastic differentiation, and secrete lactate and pyruvate (energy metabolites resulting from aerobic glycolysis). Epithelial cancer cells could then take…
Cell Cycle Template
Write in a clean editor, then format for Cell Cycle in one click — DocuGuru applies the official Taylor & Francis template with author–year references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.
About the Cell Cycle format
Cell Cycle is a peer-reviewed journal published by Taylor & Francis, covering Cancer-related Molecular Pathways, Microtubule and mitosis dynamics, DNA Repair Mechanisms.
| Publisher | Taylor & Francis |
|---|---|
| Reference style | Author–year (Chicago, T&F) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Cell Cycle 12 (3): 45–58.
Formats any DOI in Cell Cycle style. No sign-up. |
| Publishes research in | Cancer-related Molecular Pathways Microtubule and mitosis dynamics DNA Repair Mechanisms Epigenetics and DNA Methylation Genomics and Chromatin Dynamics |
| ISSN | 1538-4101 |
| Citation impact (2-yr) | 2.23 |
| h-index | 200 |
| i10-index | 6,996 |
| Total citations | 371,928 |
| Top institutions publishing here | Schlumberger (Ireland) |
| Journal website | www.tandfonline.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Cell Cycle per year
Citation impact of Cell Cycle by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in Cell Cycle
Extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) are members of the mitogen-activated protein kinase super family that can mediate cell proliferation and apoptosis. The Ras-Raf-MEK-ERK signaling cascade controlling cell proliferation has been well studied but the mechanisms involved in ERK1/2-mediated cell death are largely unknown. This review focuses on recent papers that define ERK1/2…
In a genome-wide screen for microRNAs regulated by the transcription factor encoded by the p53 tumor suppressor gene we found that after p53-activation the abundance of thirty-four miRNAs was significantly increased, whereas sixteen miRNAs were suppressed. The induction of miR-34a was most pronounced among all differential regulations. Also expression of the primary miR-34a transcript was…
As its role in tumor progression emerges, the PI3K/PKB (Akt) pathway presents an appealing cancer therapeutic target. Recent studies have investigated the mechanisms underlying the tumor-promoting effects of this pathway. PKB triggers a network that positively regulates G1/S cell cycle progression through inactivation of GSK3-beta, leading to increased cyclin D1, and inhibition of Forkhead family…
Entry and progression through mitosis has traditionally been linked directly to the activity of cyclin-dependent kinase 1 (Cdk1). In this study we utilized low doses of the Cdk1-specific inhibitor, RO3306 from early G 2 phase onwards. Addition of low doses of RO3306 in G 2 phase induced minor chromosome congression and segregation defects. In contrast,…