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EuPA Open Proteomics is a peer-reviewed journal published by Elsevier, covering Advanced Proteomics Techniques and Applications, Mass Spectrometry Techniques and Applications, Metabolomics and Mass Spectrometry Studies.
| Publisher | Elsevier |
|---|---|
| Reference style | Numbered (Elsevier) Numbered — [1], [2] in the text [1] A. Smith, B. Jones, C. Lee, A representative article title, EuPA Open Proteomics 12 (2023) 45–58.
Formats any DOI in EuPA Open Proteomics style. No sign-up. |
| Publishes research in | Advanced Proteomics Techniques and Applications Mass Spectrometry Techniques and Applications Metabolomics and Mass Spectrometry Studies Advanced Biosensing Techniques and Applications Genetics, Bioinformatics, and Biomedical Research |
| ISSN | 2212-9685 |
| h-index | 28 |
| i10-index | 71 |
| Total citations | 3,007 |
| Article processing charge | $1,700 |
| Top institutions publishing here | Ghent University |
| Journal website | www.journals.elsevier.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Citations each year’s papers have accumulated so far — the most recent years are still building up.
This minireview touches upon the challenges and opportunities peptides experience on the track to become an approved pharmaceutical. Peptide attributes originally considered troublesome with respect to drug development may now turn out to be more convenient rather than unfavourable. Besides characteristic high target affinity, biological peptides often exhibit higher than expected stability. Clearly natural selective…
We review and demonstrate how an empirical Bayes method, shrinking a protein's sample variance towards a pooled estimate, leads to far more powerful and stable inference to detect significant changes in protein abundance compared to ordinary t-tests. Using examples from isobaric mass labeled proteomic experiments we show how to analyze data from multiple experiments simultaneously,…
Peptides have been studied for over 100 years, but for most of this time the focus was on a specific peptide or peptides, and not on the general peptidome of a biological sample. In the 1990s, mass spectrometry techniques were developed for the analysis of proteins, usually after digestion into peptides. The field of peptidomics…
The parasitic nematode Anisakis simplex occurs in fish stocks in temperate seas. A. simplex contamination of fish products is unsavoury and a health concern considering human infection with live larvae (anisakiasis) and allergic reactions to anisakid proteins in seafood. Protein extracts of A. simplex produce complex band patterns in gel electrophoresis and IgE-immunostaining. In the…
SH-SY5Y neuroblastoma cells are susceptible to differentiation using retinoic acid (RA) and brain-derived neurotrophic factor (BDNF), providing a model of neuronal differentiation. We compared SH-SY5Y cells proteome before and after RA/BDNF treatment using iTRAQ and phosphopeptide enrichment strategies. We identified 5587 proteins, 366 of them with differential abundance. Differentiated cells expressed proteins related to neuronal…
