Herein we present a historical review of the development of systemic chemotherapy for colorectal cancer (CRC) in the metastatic and adjuvant treatment settings. We describe the discovery of 5-fluorouracil (5-FU) by Heidelberger and colleagues in 1957, the potentiation of 5-FU cytotoxicity by the reduced folate leucovorin, and the advent of novel cytotoxic agents, including the…
Clinical Colorectal Cancer Template
Write in a clean editor, then format for Clinical Colorectal Cancer in one click — DocuGuru applies the official Elsevier template with numbered references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.
About the Clinical Colorectal Cancer format
Clinical Colorectal Cancer is a peer-reviewed journal published by Elsevier, covering Colorectal Cancer Treatments and Studies, Colorectal Cancer Surgical Treatments, Colorectal and Anal Carcinomas.
| Publisher | Elsevier |
|---|---|
| Reference style | Numbered (Elsevier) Numbered — [1], [2] in the text [1] A. Smith, B. Jones, C. Lee, A representative article title, Clinical Colorectal Cancer 12 (2023) 45–58.
Formats any DOI in Clinical Colorectal Cancer style. No sign-up. |
| Publishes research in | Colorectal Cancer Treatments and Studies Colorectal Cancer Surgical Treatments Colorectal and Anal Carcinomas Gastric Cancer Management and Outcomes Genetic factors in colorectal cancer |
| ISSN | 1533-0028 |
| Citation impact (2-yr) | 1.5 |
| h-index | 79 |
| i10-index | 890 |
| Total citations | 35,374 |
| Article processing charge | $3,580 |
| Top institutions publishing here | Yale University |
| Journal website | www.sciencedirect.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Clinical Colorectal Cancer per year
Citation impact of Clinical Colorectal Cancer by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in Clinical Colorectal Cancer
BACKGROUND: We investigated very long-term bowel function after total mesorectal excision (TME) with or without preoperative short-course radiotherapy (PRT) for rectal cancer, the risk factors for bowel dysfunction, and the association of bowel dysfunction with health-related quality of life (HRQL). PATIENTS AND METHODS: In the TME trial (1996-1999), 1530 Dutch patients with rectal cancer were…