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Genome Biology is a peer-reviewed journal published by BMC (BioMed Central), covering Genomics and Phylogenetic Studies, Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms. Over its lifetime it has published 9,118 papers, which have received 1,114,695 citations.
| Publisher | BMC (BioMed Central) |
|---|---|
| Reference style | Numbered (Vancouver) Numbered — [1], [2] in the text 1. Smith A, Jones B, Lee C. A representative article title. Genome Biology. 2023;12(3):45–58.
Formats any DOI in Genome Biology style. No sign-up. |
| Publishes research in | Genomics and Phylogenetic Studies Genomics and Chromatin Dynamics RNA and protein synthesis mechanisms Single-cell and spatial transcriptomics RNA Research and Splicing |
| ISSN | 1465-6906 |
| Citation impact (2-yr) | 8.97 |
| h-index | 398 |
| i10-index | 5,300 |
| Article processing charge | $5,030 |
| Open access | Yes — indexed in DOAJ |
| Top institutions publishing here | Harvard University |
| Journal website | genomebiology.biomedcentral.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Citations each year’s papers have accumulated so far — the most recent years are still building up.
In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions. Small replicate numbers, discreteness, large dynamic range and the presence of outliers require a suitable statistical approach. We present DESeq2, a method for differential analysis…
Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of approximately 1.3 gigabytes. Bowtie extends previous Burrows-Wheeler techniques with a novel quality-aware backtracking algorithm that permits…
We present Model-based Analysis of ChIP-Seq data, MACS, which analyzes data generated by short read sequencers such as Solexa's Genome Analyzer. MACS empirically models the shift size of ChIP-Seq tags, and uses it to improve the spatial resolution of predicted binding sites. MACS also uses a dynamic Poisson distribution to effectively capture local biases in…
BACKGROUND: Gene-expression analysis is increasingly important in biological research, with real-time reverse transcription PCR (RT-PCR) becoming the method of choice for high-throughput and accurate expression profiling of selected genes. Given the increased sensitivity, reproducibility and large dynamic range of this methodology, the requirements for a proper internal control gene for normalization have become increasingly stringent.…
This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation. This addresses the challenge of finding organisms, genes, or pathways that consistently explain the differences between two or more microbial communities, which is a central problem to the study of…
