About the Organic Process Research & Development format
Organic Process Research & Development is a peer-reviewed journal published by American Chemical Society, covering Innovative Microfluidic and Catalytic Techniques Innovation, Chemical Synthesis and Analysis, Chemistry and Chemical Engineering. Over its lifetime it has published 6,988 papers, which have received 158,764 citations.
| Publisher | American Chemical Society |
|---|
| Reference style | Superscript numbered (ACS) Superscript — small raised numerals in the text
(1) Smith, A.; Jones, B.; Lee, C. A Representative Article Title. Organic Process Research & Development 2023, 12, 45–58.
Formats any DOI in Organic Process Research & Development style. No sign-up.
|
|---|
| Publishes research in | Innovative Microfluidic and Catalytic Techniques Innovation Chemical Synthesis and Analysis Chemistry and Chemical Engineering Analytical Chemistry and Chromatography Crystallization and Solubility Studies |
|---|
| ISSN | 1083-6160 |
|---|
| Citation impact (2-yr) | 3.24 |
|---|
| h-index | 141 |
|---|
| i10-index | 3,555 |
|---|
| Top institutions publishing here | Pfizer (United States) |
|---|
| Journal website | pubs.acs.org |
|---|
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
|---|
Papers published in Organic Process Research & Development per year
Citation impact of Organic Process Research & Development by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in Organic Process Research & Development
Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments
Kenneth L. Kirk · 26 Jan 2008
Methods for introducing fluorine into organic molecules are reviewed, with an emphasis on preparation of compounds designed for biomedicinal applications. Electrophilic fluorination, nucleophilic fluorination, and enantioselective monofluorination procedures are discussed. This is followed by a review of the development of nucleophilic and electrophilic trifluoromethylation procedures. The final sections highlight recent applications of fluorine chemistry in…
Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products
Riccardo Porta, Maurizio Benaglia, Alessandra Puglisi · 26 Nov 2015
High Resolution Image Download MS PowerPoint Slide Recently, application of the flow technologies for the preparation of fine chemicals, such as natural products or Active Pharmaceutical Ingredients (APIs), has become very popular, especially in academia. Although pharma industry still relies on multipurpose batch or semibatch reactors, it is evident that interest is arising toward continuous…
Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes
Concepción Jiménez‐González, Celia S. Ponder, Quirinus B. Broxterman et al. · 12 May 2011
There have been a many publications and much discussion about green metrics. While many have been proposed, The American Chemical Society Green Chemistry Institute’s Pharmaceutical Roundtable has chosen process mass intensity (PMI) as the key, high-level metric for evaluating and benchmarking progress towards more sustainable manufacturing. This paper provides the philosophical and technical arguments on…
Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals
Joshua R. Dunetz, Javier Magano, Gerald A. Weisenburger · 15 Nov 2015
This review showcases various coupling reagents which have been implemented specifically for large-scale amide synthesis via the condensation of an acid and amine, while highlighting the benefits and drawbacks of each reagent on an industrial scale.
Perspective on Solvent Use in the Pharmaceutical Industry
David J. C. Constable, Conchita Jimenez-Gonzalez, Richard K. Henderson · 14 Dec 2006
Solvent use consistently accounts for between 80 and 90% of mass utilization in a typical pharmaceutical/fine chemicals (non-polymer) batch chemical operation. Moreover, within these operations, solvents play a dominant role in the overall toxicity profile of any given process; i.e. on a mass basis, solvents account for the largest proportion of chemicals of concern used…
