American Chemical Society

ACS Synthetic Biology Template

Write in a clean editor, then format for ACS Synthetic Biology in one click — DocuGuru applies the official American Chemical Society template with superscript references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.

About the ACS Synthetic Biology format

ACS Synthetic Biology is a peer-reviewed journal published by American Chemical Society, covering CRISPR and Genetic Engineering, Microbial Metabolic Engineering and Bioproduction, RNA and protein synthesis mechanisms. Over its lifetime it has published 4,388 papers, which have received 120,725 citations.

PublisherAmerican Chemical Society
Reference styleSuperscript numbered (ACS)
Superscript — small raised numerals in the text
(1) Smith, A.; Jones, B.; Lee, C. A Representative Article Title. ACS Synthetic Biology 2023, 12, 45–58.

Formats any DOI in ACS Synthetic Biology style. No sign-up.

Publishes research inCRISPR and Genetic Engineering Microbial Metabolic Engineering and Bioproduction RNA and protein synthesis mechanisms Bacterial Genetics and Biotechnology Gene Regulatory Network Analysis
ISSN2161-5063
Citation impact (2-yr)4.53
h-index131
i10-index2,528
Top institutions publishing hereChinese Academy of Sciences
Journal websitepubs.acs.org
You getA submission-ready PDF and the editable LaTeX source — ready to submit.

Papers published in ACS Synthetic Biology per year

180
2014
132
2015
244
2016
280
2017
307
2018
306
2019
355
2020
372
2021
424
2022
374
2023
401
2024
473
2025

Citation impact of ACS Synthetic Biology by publication year

10.4K
2014
8.5K
2015
11.6K
2016
11.7K
2017
13K
2018
12.1K
2019
11.1K
2020
9.5K
2021
8.1K
2022
4.8K
2023
3.4K
2024
1.4K
2025

Citations each year’s papers have accumulated so far — the most recent years are still building up.

Most-cited papers in ACS Synthetic Biology

A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly

Michael E. Lee, William C. DeLoache, Bernardo Cervantes et al. · 14 Apr 2015

Saccharomyces cerevisiae is an increasingly attractive host for synthetic biology because of its long history in industrial fermentations. However, until recently, most synthetic biology systems have focused on bacteria. While there is a wealth of resources and literature about the biology of yeast, it can be daunting to navigate and extract the tools needed for…

1,050 citations Cite SaveGo to paper →
A Golden Gate Modular Cloning Toolbox for Plants

Carola Engler, Mark Youles, Ramona Gruetzner et al. · 5 Feb 2014

Plant Synthetic Biology requires robust and efficient methods for assembling multigene constructs. Golden Gate cloning provides a precision module-based cloning technique for facile assembly of multiple genes in one construct. We present here a versatile resource for plant biologists comprising a set of cloning vectors and 96 standardized parts to enable Golden Gate construction of…

1,044 citations Cite SaveGo to paper →
HOLMESv2: A CRISPR-Cas12b-Assisted Platform for Nucleic Acid Detection and DNA Methylation Quantitation

Linxian Li, Shiyuan Li, Na Wu et al. · 18 Sep 2019

-cleavage activity against collateral single-stranded DNA (ssDNA) and employed the activity to develop a rapid nucleic acid detection system, namely HOLMES (one-hour low-cost multipurpose highly efficient system). Here, with the employment of thermophilic CRISPR-Cas12b, we create HOLMESv2 for four different applications: (1) specifically discriminating single nucleotide polymorphism (SNP); (2) simply detecting virus RNA, human cell…

High-Efficiency Multiplex Genome Editing of <i>Streptomyces</i> Species Using an Engineered CRISPR/Cas System

Ryan E. Cobb, Yajie Wang, Huimin Zhao · 2 Dec 2014

Actinobacteria, particularly those of genus Streptomyces, remain invaluable hosts for the discovery and engineering of natural products and their cognate biosynthetic pathways. However, genetic manipulation of these bacteria is often labor and time intensive. Here, we present an engineered CRISPR/Cas system for rapid multiplex genome editing of Streptomyces strains, demonstrating targeted chromosomal deletions in three…

The All <i>E. coli</i> TX-TL Toolbox 2.0: A Platform for Cell-Free Synthetic Biology

Jonathan Garamella, Ryan Marshall, Mark Rustad et al. · 28 Jan 2016

We report on and provide a detailed characterization of the performance and properties of a recently developed, all Escherichia coli, cell-free transcription and translation system. Gene expression is entirely based on the endogenous translation components and transcription machinery provided by an E. coli cytoplasmic extract, thus expanding the repertoire of regulatory parts to hundreds of…

ACS Synthetic Biology template — frequently asked questions

How do I write a paper in the ACS Synthetic Biology format?
In DocuGuru you write your manuscript in a normal editor — no LaTeX setup required — and select the ACS Synthetic Biology template. When you export, DocuGuru compiles the paper into the official American Chemical Society format and hands you a submission-ready PDF along with the editable LaTeX source.
What reference style does ACS Synthetic Biology use?
ACS Synthetic Biology uses Superscript numbered (ACS) references, shown as superscript numerals in the text. DocuGuru formats every in-text citation and the reference list in this exact style automatically. A reference appears like this: (1) Smith, A.; Jones, B.; Lee, C. A Representative Article Title. ACS Synthetic Biology 2023, 12, 45–58.
Do I need to know LaTeX to submit to ACS Synthetic Biology?
No. DocuGuru generates the achemso LaTeX class and compiles the PDF for you in the background, so you get a American Chemical Society-ready ACS Synthetic Biology document without writing any LaTeX. If you do want it, the LaTeX source is included in the export.
Can I import an existing draft into the ACS Synthetic Biology template?
Yes. Paste or upload your current manuscript — Word, LaTeX, Markdown, or plain text — and DocuGuru reflows it into the ACS Synthetic Biology format with correct headings, figures, tables, and superscript citations.
What is ACS Synthetic Biology?
ACS journal (achemso). It is a chemistry journal, published by American Chemical Society.
Can I export a submission-ready ACS Synthetic Biology PDF?
Yes — DocuGuru produces a PDF built with the official ACS Synthetic Biology template (the achemso class) that is ready to submit to American Chemical Society, together with the matching LaTeX source files.
How much does the ACS Synthetic Biology template cost?
You can start writing in the ACS Synthetic Biology template for free. Exporting the final submission-ready ACS Synthetic Biology PDF and LaTeX source is part of DocuGuru's paid plans — see the app for current pricing.
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