Abstract A convenient method for the synthesis of 18 F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and 18 F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with 18 F‐F 2 is described. 14 C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from 14 C‐3,4,6‐tri‐0‐acetyl‐D‐glucal (from D‐[ 14 c(U)]‐glucose) by fluorination with F 2 (Method 1) and CF 3 OF (Method 2). These labeled analogs…
Journal of Labelled Compounds and Radiopharmaceuticals Template
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Journal of Labelled Compounds and Radiopharmaceuticals is a peer-reviewed journal published by Wiley, covering Radiopharmaceutical Chemistry and Applications, Chemical Reactions and Isotopes, Medical Imaging Techniques and Applications.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Journal of Labelled Compounds and Radiopharmaceuticals 12 (3): 45–58.
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| Publishes research in | Radiopharmaceutical Chemistry and Applications Chemical Reactions and Isotopes Medical Imaging Techniques and Applications Chemical Synthesis and Analysis Synthesis and Biological Evaluation |
| ISSN | 0362-4803 |
| Citation impact (2-yr) | 0.55 |
| h-index | 67 |
| i10-index | 1,475 |
| Total citations | 51,339 |
| Article processing charge | $3,450 |
| Top institutions publishing here | Commissariat à l'Énergie Atomique et aux Énergies Alternatives |
| Journal website | onlinelibrary.wiley.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
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Most-cited papers in Journal of Labelled Compounds and Radiopharmaceuticals
Abstract Aromatic nucleophilic substitution of various trimethylammonium trifluoromethanesulfonates with [ 18 F]fluoride has been evaluated. Fluorinations were studied over a temperature range of 45–165°C, with decay corrected yields ranging from 20–80%. [ 18 F]GBR 13119, 1‐[2‐{(4‐[ 18 F]fluorophenyl)(phenyl)methoxy}ethyl]‐4‐(3‐phenylpropyl)piperazine, a potential radio‐tracer for the dopamine uptake system, has been prepared in no‐carrier‐added form from 4‐N,N,N,‐trimethylaniliniumphenylmethanone trifluoromethanesulfonate.…
Abstract This review addresses method developments both homogeneous and heterogeneous Pd‐ and Pt‐catalyzed exchange, including catalyst activation principles and recent practical applications together with example procedures. Specific requirements for isotopically labelled internal MS standard preparation are discussed from a Sanofi‐Aventis perspective on recent examples. Copyright © 2010 John Wiley & Sons, Ltd.
Technetium‐99m ( 99m Tc) is a widely used radionuclide, and the development of 99m Tc imaging agents continues to be in demand. This overview discusses basic principles of 99m Tc radiopharmaceutical preparation and design and focuses on the 99m Tc radiochemistry relevant to its pharmaceutical applications. The 99m Tc complexes are described based on the…
Abstract N‐( 11 c) methyl, N‐(methyl‐1 propyl), (chloro‐2 phenyl)‐1 isoquinoleine carboxamide‐3 (PK 11195) or ( 11 C) MPCI was synthetized in a short time (45 min) and high specific activity (769 Ci/mmo 1) for the positron emission tomography of peripheral benzodiazepine receptors in heart, kidney and brain. The precursor used was the N‐desmethyl MPCI (PCI).…