Statins are the treatment of choice for the management of hypercholesterolaemia because of their proven efficacy and safety profile. They also have an increasing role in managing cardiovascular risk in patients with relatively normal levels of plasma cholesterol. Although all statins share a common mechanism of action, they differ in terms of their chemical structures,…
Fundamental and Clinical Pharmacology Template
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About the Fundamental and Clinical Pharmacology format
Fundamental and Clinical Pharmacology is a peer-reviewed journal published by Wiley, covering Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Nitric Oxide and Endothelin Effects.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Fundamental and Clinical Pharmacology 12 (3): 45–58.
Formats any DOI in Fundamental and Clinical Pharmacology style. No sign-up. |
| Publishes research in | Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology Research Nitric Oxide and Endothelin Effects Ion channel regulation and function Cardiac electrophysiology and arrhythmias |
| ISSN | 0767-3981 |
| Citation impact (2-yr) | 1.73 |
| h-index | 102 |
| i10-index | 1,576 |
| Total citations | 66,392 |
| Article processing charge | $2,990 |
| Top institutions publishing here | Inserm |
| Journal website | onlinelibrary.wiley.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Fundamental and Clinical Pharmacology per year
Citation impact of Fundamental and Clinical Pharmacology by publication year
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Most-cited papers in Fundamental and Clinical Pharmacology
The Hill equation was first introduced by A.V. Hill to describe the equilibrium relationship between oxygen tension and the saturation of haemoglobin. In pharmacology, the Hill equation has been extensively used to analyse quantitative drug-receptor relationships. Many pharmacokinetic-pharmacodynamic models have used the Hill equation to describe nonlinear drug dose-response relationships. Although the Hill equation is…
Gadolinium-based contrast agents (CAs) are widely used to enhance the contrast of images in magnetic resonance imaging procedures. Two categories of gadolinium chelates exist: the macrocyclic molecules where Gd3+ is caged in the pre-organized cavity of the ligand and the linear molecules. Gadolinium chelates differ in their thermodynamic stability constants and in their kinetic stability.…
Animal models are pivotal for understanding the mechanism of neuropathic pain and development of effective therapy for its optimal management. A battery of neuropathic pain models has been developed to simulate the clinical pain conditions with diverse etiology. The present review exhaustively discusses the methodology, behavioral alterations, limitations, and advantages of about 40 different animal…
Reactive oxygen species contribute decisively to a great variety of diseases. Flavonoids are benzo-gamma-pyrone derivatives of plant origin found in various fruits and vegetables but also in tea and in red wine. Some of the flavonoids, such as quercetin and silibinin, can effectively protect cells and tissues against the deleterious effects of reactive oxygen species.…