Interleukin-10 (IL-10) has been described as an anti-inflammatory cytokine and B-cell proliferation factor and has been implicated in autoimmunity, tumorigenesis and transplantation tolerance. We have identified three single base pair substitutions in the IL-10 gene promoter and have investigated whether this polymorphism correlates with IL-10 protein production in vitro.
European Journal of Immunogenetics Template
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About the European Journal of Immunogenetics format
European Journal of Immunogenetics is a peer-reviewed journal published by Wiley, covering T-cell and B-cell Immunology, Immune Cell Function and Interaction, Cytomegalovirus and herpesvirus research.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." European Journal of Immunogenetics 12 (3): 45–58.
Formats any DOI in European Journal of Immunogenetics style. No sign-up. |
| Publishes research in | T-cell and B-cell Immunology Immune Cell Function and Interaction Cytomegalovirus and herpesvirus research Immunotherapy and Immune Responses Immunodeficiency and Autoimmune Disorders |
| ISSN | 0960-7420 |
| h-index | 46 |
| i10-index | 218 |
| Total citations | 10,087 |
| Top institutions publishing here | Anthony Nolan |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in European Journal of Immunogenetics per year
Citation impact of European Journal of Immunogenetics by publication year
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Most-cited papers in European Journal of Immunogenetics
The DNA sequence of the human IFN-gamma gene shows the presence of a variable-length CA repeat in the first intron of the gene. We investigated the allele distribution of this microsatellite region in 164 unrelated healthy individuals, and the association with interferon-gamma (IFN-gamma) production. In vitro production of IFN-gamma showed a significant correlation with the…
Recently a number of new genes have been identified within the HLA region including some whose functions are related to HLA Class I and II genes.The committee discussed what its strategy should be for the naming of these and further new genes.It concluded that the naming of such genes raised many new issues and that…
Single nucleotide polymorphisms (SNPs) in the promoter regions of cytokine genes are associated with differential levels of cytokine expression. We hypothesized that these SNPs might influence breast tumour development and progression by affecting the efficiency of the antitumour immune response and/or pathways of angiogenesis. A total of 144 female breast cancer patients and 263 cancer-free…
In the light of the key role played by interferon (IFN)-gamma in the control of tuberculosis, in the present paper we have evaluated the distribution of the functional +874T --> A IFN-gamma single nucleotide polymorphism (SNP) in Sicilian patients affected by tuberculosis. Our aim was to determine whether there is an association between the TT…