Abstract GW Pharmaceuticals’ formulation of highly purified cannabidiol oral solution is approved in the United States for seizures associated with Lennox‐Gastaut and Dravet syndromes in patients aged ≥2 years, for which clobazam, stiripentol, and valproate are commonly used antiepileptic drugs. This open‐label, fixed‐sequence, drug‐drug interaction, healthy volunteer trial investigated the impact of cannabidiol on steady‐state…
Clinical Pharmacology in Drug Development Template
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About the Clinical Pharmacology in Drug Development format
Clinical Pharmacology in Drug Development is a peer-reviewed journal published by Wiley, covering Pharmaceutical studies and practices, Pharmacogenetics and Drug Metabolism, Diabetes Treatment and Management.
| Publisher | Wiley |
|---|---|
| Reference style | Author–year (Chicago) Author–year — (Smith, 2023) in the text Smith, Ada, Ben Jones, and Cara Lee. 2023. "A Representative Article Title." Clinical Pharmacology in Drug Development 12 (3): 45–58.
Formats any DOI in Clinical Pharmacology in Drug Development style. No sign-up. |
| Publishes research in | Pharmaceutical studies and practices Pharmacogenetics and Drug Metabolism Diabetes Treatment and Management Drug Transport and Resistance Mechanisms Chronic Lymphocytic Leukemia Research |
| ISSN | 2160-763X |
| Citation impact (2-yr) | 1.31 |
| h-index | 46 |
| i10-index | 450 |
| Total citations | 14,167 |
| Article processing charge | $3,450 |
| Top institutions publishing here | Pfizer (United States) |
| Journal website | accp1.onlinelibrary.wiley.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Clinical Pharmacology in Drug Development per year
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Most-cited papers in Clinical Pharmacology in Drug Development
BACKGROUND: Edoxaban is an oral, once-daily, direct factor Xa inhibitor under investigation for stroke prevention in patients with atrial fibrillation and for treatment and secondary prevention of venous thromboembolism. This study evaluated edoxaban absolute bioavailability and effects of the P-glycoprotein inhibitor quinidine on edoxaban pharmacokinetics after intravenous edoxaban administration. METHODS: Healthy volunteers received three treatments…
Empagliflozin is an orally available, selective inhibitor of sodium glucose cotransporter 2. In this study, single oral doses of empagliflozin from 0.5 to 800 mg were not associated with any clinically significant safety concerns in healthy male volunteers. The incidence of adverse events (AEs) was similar in subjects receiving placebo (22.2%) or empagliflozin (25.0%) in…
Abstract This report summarizes phase 1 studies that evaluated pharmacokinetic interactions between the novel triazole antifungal agent isavuconazole and the immunosuppressants cyclosporine, mycophenolic acid, prednisolone, sirolimus, and tacrolimus in healthy adults. Healthy subjects received single oral doses of cyclosporine (300 mg; n = 24), mycophenolate mofetil (1000 mg; n = 24), prednisone (20 mg; n…
Abstract This report describes the phase 1 trials that evaluated the metabolism of the novel triazole antifungal isavuconazole by cytochrome P450 3A4 (CYP3A4) and isavuconazole's effects on CYP3A4‐mediated metabolism in healthy adults. Coadministration of oral isavuconazole (100 mg once daily) with oral rifampin (600 mg once daily; CYP3A4 inducer) decreased isavuconazole area under the concentration‐time…