Frontiers

Frontiers in Systems Biology Template

Write in a clean editor, then format for Frontiers in Systems Biology in one click — DocuGuru applies the official Frontiers template with author–year references and exports a submission-ready PDF plus the editable LaTeX source. Free to start.

About the Frontiers in Systems Biology format

Frontiers in Systems Biology is a peer-reviewed journal published by Frontiers, covering Gene Regulatory Network Analysis, Bioinformatics and Genomic Networks, Computational Drug Discovery Methods. Over its lifetime it has published 199 papers, which have received 1,225 citations.

PublisherFrontiers
Reference styleAuthor–year (Harvard)
Author–year — (Smith, 2023) in the text
Smith, A., Jones, B. and Lee, C. (2023) 'A representative article title', Frontiers in Systems Biology, 12(3), pp. 45–58.

Formats any DOI in Frontiers in Systems Biology style. No sign-up.

Publishes research inGene Regulatory Network Analysis Bioinformatics and Genomic Networks Computational Drug Discovery Methods Microbial Metabolic Engineering and Bioproduction Gut microbiota and health
ISSN2674-0702
Citation impact (2-yr)3.28
h-index17
i10-index34
Open accessYes — indexed in DOAJ
Top institutions publishing hereUniversity of Pittsburgh
You getA submission-ready PDF and the editable LaTeX source — ready to submit.

Papers published in Frontiers in Systems Biology per year

1
2012
7
2021
46
2022
42
2023
45
2024
28
2025

Citation impact of Frontiers in Systems Biology by publication year

0
2012
25
2021
526
2022
320
2023
234
2024
79
2025

Citations each year’s papers have accumulated so far — the most recent years are still building up.

Most-cited papers in Frontiers in Systems Biology

A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration

Jelissa Reynoso-García, Angel E. Miranda-Santiago, Natalie M. Meléndez-Vázquez et al. · 22 Jul 2022

Humans are supra-organisms co-evolved with microbial communities (Prokaryotic and Eukaryotic), named the microbiome. These microbiomes supply essential ecosystem services that play critical roles in human health. A loss of indigenous microbes through modern lifestyles leads to microbial extinctions, associated with many diseases and epidemics. This narrative review conforms a complete guide to the human holobiont-comprising…

Batch correction and harmonization of –Omics datasets with a tunable median polish of ratio

Eric B. Dammer, Nicholas T. Seyfried, Erik C. B. Johnson · 12 Apr 2023

Large scale -omics datasets can provide new insights into normal and disease-related biology when analyzed through a systems biology framework. However, technical artefacts present in most -omics datasets due to variations in sample preparation, batching, platform settings, personnel, and other experimental procedures prevent useful analyses of such data without prior adjustment for these technical factors.…

Drug Development Digital Twins for Drug Discovery, Testing and Repurposing: A Schema for Requirements and Development

Gary An, Chase Cockrell · 20 Jun 2022

There has been a great deal of interest in the concept, development and implementation of medical digital twins. This interest has led to wide ranging perceptions of what constitutes a medical digital twin. This Perspectives article will provide 1) a description of fundamental features of industrial digital twins, the source of the digital twin concept,…

The rise of scientific machine learning: a perspective on combining mechanistic modelling with machine learning for systems biology

Ben Noordijk, Monica L. Garcia Gomez, Kirsten ten Tusscher et al. · 2 Aug 2024

Both machine learning and mechanistic modelling approaches have been used independently with great success in systems biology. Machine learning excels in deriving statistical relationships and quantitative prediction from data, while mechanistic modelling is a powerful approach to capture knowledge and infer causal mechanisms underpinning biological phenomena. Importantly, the strengths of one are the weaknesses of…

A practical guide for the generation of model-based virtual clinical trials

Morgan Craig, Jana L. Gevertz, Irina Kareva et al. · 16 Jun 2023

Mathematical modeling has made significant contributions to drug design, development, and optimization. Virtual clinical trials that integrate mathematical models to explore patient heterogeneity and its impact on a variety of therapeutic questions have recently risen in popularity. Here, we outline best practices for creating virtual patients from mathematical models to ultimately implement and execute a…

Frontiers in Systems Biology template — frequently asked questions

How do I write a paper in the Frontiers in Systems Biology format?
In DocuGuru you write your manuscript in a normal editor — no LaTeX setup required — and select the Frontiers in Systems Biology template. When you export, DocuGuru compiles the paper into the official Frontiers format and hands you a submission-ready PDF along with the editable LaTeX source.
What reference style does Frontiers in Systems Biology use?
Frontiers in Systems Biology uses Author–year (Harvard) references, shown as author–year markers such as (Smith, 2023) in the text. DocuGuru formats every in-text citation and the reference list in this exact style automatically. A reference appears like this: Smith, A., Jones, B. and Lee, C. (2023) 'A representative article title', Frontiers in Systems Biology, 12(3), pp. 45–58.
Do I need to know LaTeX to submit to Frontiers in Systems Biology?
No. DocuGuru generates the FrontiersinHarvard LaTeX class and compiles the PDF for you in the background, so you get a Frontiers-ready Frontiers in Systems Biology document without writing any LaTeX. If you do want it, the LaTeX source is included in the export.
Can I import an existing draft into the Frontiers in Systems Biology template?
Yes. Paste or upload your current manuscript — Word, LaTeX, Markdown, or plain text — and DocuGuru reflows it into the Frontiers in Systems Biology format with correct headings, figures, tables, and author–year citations.
What is Frontiers in Systems Biology?
Frontiers journal. It is a life sciences and medicine journal, published by Frontiers.
Can I export a submission-ready Frontiers in Systems Biology PDF?
Yes — DocuGuru produces a PDF built with the official Frontiers in Systems Biology template (the FrontiersinHarvard class) that is ready to submit to Frontiers, together with the matching LaTeX source files.
How much does the Frontiers in Systems Biology template cost?
You can start writing in the Frontiers in Systems Biology template for free. Exporting the final submission-ready Frontiers in Systems Biology PDF and LaTeX source is part of DocuGuru's paid plans — see the app for current pricing.
Use the Frontiers in Systems Biology template