BACKGROUND: The identification and characterisation of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in epigenetics. We present a novel method, DMRcate, that fits replicated methylation measurements from the Illumina HM450K BeadChip (or 450K array) spatially across the genome using a Gaussian kernel. DMRcate identifies and ranks the most…
Epigenetics & Chromatin Template
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About the Epigenetics & Chromatin format
Epigenetics & Chromatin is a peer-reviewed journal published by BMC (BioMed Central), covering Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, Chromosomal and Genetic Variations. Over its lifetime it has published 1,047 papers, which have received 39,305 citations.
| Publisher | BMC (BioMed Central) |
|---|---|
| Reference style | Numbered (Vancouver) Numbered — [1], [2] in the text 1. Smith A, Jones B, Lee C. A representative article title. Epigenetics & Chromatin. 2023;12(3):45–58.
Formats any DOI in Epigenetics & Chromatin style. No sign-up. |
| Publishes research in | Genomics and Chromatin Dynamics Epigenetics and DNA Methylation Chromosomal and Genetic Variations Cancer-related gene regulation Genetic Syndromes and Imprinting |
| ISSN | 1756-8935 |
| Citation impact (2-yr) | 5.3 |
| h-index | 93 |
| i10-index | 649 |
| Article processing charge | $2,318 |
| Open access | Yes — indexed in DOAJ |
| Top institutions publishing here | Centre National de la Recherche Scientifique |
| Journal website | link.springer.com |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Epigenetics & Chromatin per year
Citation impact of Epigenetics & Chromatin by publication year
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Most-cited papers in Epigenetics & Chromatin
BACKGROUND: CUT&RUN is an efficient epigenome profiling method that identifies sites of DNA binding protein enrichment genome-wide with high signal to noise and low sequencing requirements. Currently, the analysis of CUT&RUN data is complicated by its exceptionally low background, which renders programs designed for analysis of ChIP-seq data vulnerable to oversensitivity in identifying sites of…
Constitutive heterochromatin, mainly formed at the gene-poor regions of pericentromeres, is believed to ensure a condensed and transcriptionally inert chromatin conformation. Pericentromeres consist of repetitive tandem satellite repeats and are crucial chromosomal elements that are responsible for accurate chromosome segregation in mitosis. The repeat sequences are not conserved and can greatly vary between different organisms,…
BACKGROUND: Measurement of genome-wide DNA methylation (DNAm) has become an important avenue for investigating potential physiologically-relevant epigenetic changes. Illumina Infinium (Illumina, San Diego, CA, USA) is a commercially available microarray suite used to measure DNAm at many sites throughout the genome. However, it has been suggested that a subset of array probes may give misleading…
Transcriptional activation throughout the eukaryotic lineage has been tightly linked with disruption of nucleosome organization at promoters, enhancers, silencers, insulators and locus control regions due to transcription factor binding. Regulatory DNA thus coincides with open or accessible genomic sites of remodeled chromatin. Current chromatin accessibility assays are used to separate the genome by enzymatic or…