Lipofuscin is membrane-bound cellular waste that can be neither degraded nor ejected from the cell but can only be diluted through cell division and subsequent growth. The fate of postmitotic cells is to accumulate lipofuscin, which as an "aging pigment" has been considered a reliable biomarker for the age of cells such as neurons and,…
Science of Aging Knowledge Environment Template
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About the Science of Aging Knowledge Environment format
Science of Aging Knowledge Environment is a peer-reviewed journal published by AAAS (Science), covering Genetics, Aging, and Longevity in Model Organisms, Technology Use by Older Adults, Mitochondrial Function and Pathology.
| Publisher | AAAS (Science) |
|---|---|
| Reference style | Superscript numbered (Science) Superscript — small raised numerals in the text 1. A. Smith, B. Jones, C. Lee, A representative article title. Science of Aging Knowledge Environment 12, 45–58 (2023).
Formats any DOI in Science of Aging Knowledge Environment style. No sign-up. |
| Publishes research in | Genetics, Aging, and Longevity in Model Organisms Technology Use by Older Adults Mitochondrial Function and Pathology Adipose Tissue and Metabolism Alzheimer's disease research and treatments |
| ISSN | 1539-6150 |
| h-index | 43 |
| i10-index | 123 |
| Total citations | 7,126 |
| Top institutions publishing here | Columbia University |
| Journal website | sageke.sciencemag.org |
| You get | A submission-ready PDF and the editable LaTeX source — ready to submit. |
Papers published in Science of Aging Knowledge Environment per year
Citation impact of Science of Aging Knowledge Environment by publication year
Citations each year’s papers have accumulated so far — the most recent years are still building up.
Most-cited papers in Science of Aging Knowledge Environment
This 1956 paper describes a theory about mechanisms of aging that is based on free radical chemistry: "Aging and the degenerative diseases associated with it are attributed basically to the deleterious side attacks of free radicals on cell constituents and on the connective tissues. The free radicals probably arise largely through reactions involving molecular oxygen…
Females live longer than males in many species, including humans. We have traced a possible explanation for this phenomenon to the beneficial action of estrogens, which bind to estrogen receptors and increase the expression of longevity-associated genes, including those encoding the antioxidant enzymes superoxide dismutase and glutathione peroxidase. As a result, mitochondria from females produce…
Caloric restriction has resulted in a consistent robust increase in the maximal length of life in mammalian species. This article reviews significant advances over the long history of research on calorie restriction and longevity.
A new individual entering a population may be said to have a reproductive probability distribution. The reproductive probability is zero from zygote to reproductive maturity. Later, perhaps shortly after maturity, it reaches a peak value. Then it declines because of the cumulative probability of death. There is a cumulative probability of death with or without…